The Medical Letter on Drugs and Therapeutics
FROM
ISSUE1106
ISSUE1106
June 11, 2001
Clarification: Drug Risk in Patients with Glaucoma
Med Lett Drugs Ther. 2001 Jun 11;43(1106):52
Disclosures
Objective(s)
SUMMARY: The Medical Letter article on Detrol LA and Ditropan XL (vol.43, page 28, April 2, 2001) stated that these drugs should not be used in patients with glaucoma. That statement is misleading because anticholinergic or antimuscarinic drugs present a risk only to patients with untreated angle-closure (also called narrow-angle) glaucoma, which accounts for 10% of glaucomas in the USA. These drugs have no effect on the more common open-angle glaucoma, or on angle-closure glaucoma that has been treated by laser iridectomy.
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